Researchers found that a dietary supplement called glucosamine helped to reduce neural excitability in rodents.

A new study reveals how a dietary supplement could be used to reduce excitability in brain cells " a known trigger of seizures " opening the door to possible new treatments for epilepsy.

Researchers speculated that reductions in a protein modification called O-GlcNAcylation in the brain cells of rats and mice might lead to neural excitability, which is a known trigger of seizures.

In the new study, increasing levels of this protein with glucosamine " which is a supplement used to help reduce pain in osteoarthritis, among other conditions " was found to reduce neural excitability in rodents.

The findings not only help to shed light on the processes behind neural excitability, but they may also have identified a new treatment target for epilepsy.

Study co-author Prof. John Chatham, of the Department of Pathology at the University of Alabama at Birmingham, and colleagues recently reported their findings in The Journal of Neuroscience.

Epilepsy is a neurological disorder that is estimated to affect around 3 million adults and 470,000 children in the United States.

The condition is characterized by unpredictable, recurrent seizures, which can occur when brain cells become hyperactive. This may cause surges of electrical activity that disrupt signaling between brain cells.

In a previous study, Prof. Chatham and team found that increases in protein O-GlcNAcylation are associated with a reduction in the strength of synapses in the hippocampus of the brain. Synapses are structures that allow neurons to transmit signals to each other.

The team notes that neural excitability in the hippocampus " or the learning and memory region of the brain " is often implicated in people with epilepsy.

Given their previous findings, the researchers hypothesized that increasing O-GlcNAcylation levels could help to reduce neural excitability, thereby preventing seizures.

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About Us

Speak to anyone who has experienced the PROCESS of buying or selling Real Estate and often their findings are a combination of stress, disappointment and ultimately compromise! One of my many goals is to ensure your next move is a positive one.

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Vandaag, hebben bijna verschillende bedrijven een stapje verder in de richting van de groei en het succes door hun producten en diensten online beschikbaar maken. Met dit soort strategie, consumenten kunnen nu toegang tot de producten en diensten op hun gemak altijd en overal.

Zelfs taxi en chauffeur van bedrijven zoals Tokyo MK Taxi heeft het mogelijk gemaakt voor hun cliënten om te boeken en huren van personenauto's met hun smartphone en laptops. Met de verenigbaarheid ervan met verschillende platforms, verzekeren dat onze dienst efficiënt onder alle omstandigheden werken zal. Als u op zoek bent voor een taxi of de auto beschikbaar is in de buurt van u, kunt u gebruikmaken van onze PC's (Privé Chauffeur Service) te vinden van taxi's toegankelijk voor huren in de buurt van uw locatie.

Met deze vorm van dienstverlening, om verzoekt, de taxi zal worden gedoe gratis voor de klanten van Tokyo MK Taxi, als ze kunnen gemakkelijk bereiken van het stuurprogramma en het maken van hun reis in de aanleg. Registratie is eenvoudig, zodra u registreren, u selecteert 'huidige locatie' en naar een nabijgelegen taxi's zoeken. Uw 'locatie' kan direct via 'GPS zoeken' voor GPS toegelaten telefoons worden bevestigd. U kunt direct bellen het stuurprogramma door het kiezen van het weergegeven getal en brengen de klantnaam en locatie.

Wij bieden voordelige taxiservice zonder afbreuk te doen aan de kwaliteit van de dienstverlening van de klant. Wij begrijpen het belang van client-centered dienst. Om deze reden bieden wij een luxe rit ervaring op een van de vele voertuigen in onze vloot. Tokyo MK Taxi functies Lexus groep liefhebbers state-of-the-art vloot samen met een scala aan luxe voertuigen uit sedans minibusjes zodat u kunt er zeker van te vinden die bij u past reizen behoeften.