For the first time, a collaborative team led by The University of Texas Medical Branch at Galveston has shown that a potential Zika vaccine quickly can protect fetuses against infection as well as protect males against testicular infection and injury. It also prevents a lowered sperm count after one vaccination. The findings are currently available in Nature Communications.

Although Zika infection typically results in mild or symptom-free infections in healthy individuals, infected pregnant women without symptoms may still give birth to a baby with birth defects like microcephaly. Similarly, infected men without noticeable signs of illness may still incur testicular injury and lowered sperm count. The Zika virus could infect the male reproductive system for several months, posing risk for sexual transmission.

“This study showed, for the first time, that a single-dose vaccine candidate could prevent Zika infection in non-human primates, block mother-to-fetus transmission, and stop male testis infection in mice,” said UTMB’s Pei-Yong Shi, senior author and the I.H. Kempner professor at the department of biochemistry and molecular biology. “Besides quickly mounting a protective immune response, this live-attenuated vaccine exhibited an excellent safety profile in both mouse and non-human primate models. Taken together, the results suggest that this vaccine merits further development in humans.”

“Having a Zika vaccine that can protect male reproductive systems, pregnant women and their unborn babies would improve public health efforts to avoid birth defects and other effects of the disease in regions where Zika is circulating,” said Pedro Vasconcelos, director of Evandro Chagas Institute in Brazil and co-developer of this vaccine. “It’s important to note that a single-dose vaccine is practically important; vaccines that require booster shots are impractically challenging for people living in developing regions where access to medical facilities may be limited.”

Other authors include UTMB’s Chao Shan, Antonio Muruato, Bruno Nunes, Daniele Medeiros, Xuping Xie, Jannyce Nunes, Alan Barrett, Scott Weaver and Shannan Rossi; Justin Richner, Brett Jagger and Michael Diamond from Washington University School of Medicine; Kaitlyn Morabito, Wing-Pui Kong, Barney Graham and Theodore Pierson from the National Institutes of Health as well as Pedro Vasconcelos from Evandro Chagas Institute, Ministry of Health, Parå State University, Brazil.

The National Institutes of Health, UTMB, The University of Texas System, The Centers for Disease Control and Prevention, the Pan American Health Organization and the Kleberg Foundation, supported this work.

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Known as the “Wall Street of the Southwest”, Galveston Island boasts an abundance of Gulf beaches, architectural jewels and grand mansions. People flock in this 32 miles long island for a lot of reasons, mostly for enjoyment, relaxation and adventure.

Where to Stay

Oftentimes, the location of the hotel you would want to stay is a big factor while on the island. Good thing, there are numerous hotels and lodges near the center of the island and top attractions. Whether you are planning to travel with your family, there are numerous family-friendly houses and condos that will fit your budget. Do some research to find the perfect place suited to your needs.

Historic Places

While visiting Galveston, make sure to explore the beautiful historic homes they are famous for, including the 1859 Ashton Villa, the Bishop’s Palace which is built in 1892 and the famous 1895 Moody Mansion which portrays early 20th-century family life among Galveston’s elite.

Some of the must-see sites in the island includes The Grand 1894 Opera House, Texas Seaport Museum and the Moody Gardens.

Galveston’s Downtown

Don’t miss the opportunity to visit Galveston’s historic downtown district where more than 100 unique shops, restaurants, galleries and museums can be found. The Strand, a National Historic Landmark is widely considered the island’s shopping and entertainment center. Take some time to explore a variety of shops in the district and visit fine restaurants that offer everything from Greek and Mexican to Italian foods, most especially fresh Gulf seafood.

Learn about the past by exploring a variety of museums that features Galveston’s rich history such as the maritime Texas Seaport Museum and 1877 Tall Ship ELISSA.

Business Plans at Galveston

Galveston isn’t just a vacation destination, it can also be an excellent place to conduct business meetings. Make your next meeting far from ordinary, let the Galveston Island Convention & Visitors Bureau assist with your planning needs.


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Relying on the expertise of a car servicing company could give you the assurance that your car is in good hands. Gaining benefits and quality car maintenance and repair are also not new in this endeavor. Provided in the following are some benefits of having the services of a car servicing company:

Durability

To longer the lifespan of your car, you need to keep your machines clean all the time to ensure its durability. This way, you could steer clear of unwanted rusts in your car as well as chinks in your engine. If the weather is bad such as there's a heavy snow or rain, then you should thoroughly clean your car, but not just during these times, regular cleaning of your automobile is also advised. To always ensure the good condition of your car, it would be better to ask the help of professionals.

High value

In the long run, a well-maintained car will definitely have a high resale value. You can ask a car servicing company such as the Tyre&Auto Southbourne Group to keep detailed and up-to-date maintenance records. By doing this, you'll also get regular reminders that will advise you to perform the required and scheduled tasks on time.

Budget friendly

We say budget friendly because a car servicing company can help you avoid any huge problems in your car, and when we say big problems then it involves a lot of expenses on your side. Cars are not perfect machines after all because they might have some faults later on such as defects caused by the weather or constant use. A professional can better identify those problems and can handle any minor problems in advance before they become major ones.

Technical expertise

Many car owners entrust their cars to a car servicing company such as the Tyre&Auto Southbourne Group because they have the required technical skills and tools that an ordinary car owner doesn't have. They allow such companies do wheel-balancing, electrical repairs or ignition timing on their cars.

Record-keeping

Let a car servicing company take care of your car's maintenance and repair log. By doing this, they could have further value in the coming years.

Car servicing companies such as the Tyre&Auto Southbourne Group encourages customers to concentrate on more productive activities than worrying themselves about the condition of their cars since such companies could better handle all the aspects involved in taking care of automobiles

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Adverse decision inKentucky could embolden crash rings

A Kentucky lower court has thrown a wrench in the campaignto combat the growing scams involving PIP crashes in the Bluegrass State. Thecourt agreed with two claimants in an auto crash. They’re suspected of fraud.Insurers have no right to compel them to attend an examination under oath(EUO), the lower court ruled.

The Coalitionand NICB filed an amicus brief this week asking the Kentucky Supreme Court tooverturn the decision and restore insurer rights to use EUOs.

EUOs are a powerful weapon to get at the truth. Whensummoned, many fraudstersdon’t bother showing up —especially lower-level ring members. They feel the fewdollars they’re making don’t offset the potential of getting caught.

EUOs are a deterrent as well. Knowing there’s a chance youmight have to give details of a claim under oath helps keep people honest.

Take the EUO away, and more fraud rings likely will escapedetection and feel emboldened to commit more fraud.

The Kentucky claimants contend insurers use EUOs to harassand intimidate honest claimants. We’ve found no evidence to support thiscontention. We determined that insurers use EUOs very infrequently, and onlywhen necessary to discover truth about a claim.

In fact, EUOs can be an important tool to validatelegitimate claims.

Sometime later this year, the Kentucky Supreme Court willannounce its decision. Here’s hoping they support uncovering the truth aboutpotentially fraudulent auto claims.

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